Willpower as the Key to Success?

And those indications need to be promising enough for pharmaceutical companies to partner with us or buy daughter companies from us as we move from the phase-one trial to phase two. One of the things that set Life Biosciences apart from other companies is that we want everyone to be …

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Belief that others are better than you

How the TAME Study Works Overseen by the American Federation for Aging Research (AFAR), TAME is a six-year, double-blind, placebo-controlled trial in which we have enrolled a diverse population of about three thousand adults, ages sixty-five to eighty, who do not have diabetes but who have begun to contract age-related …

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Elaborate and Rehearse

A week later, AFAR informed me that he believed in our research and wanted to contribute a significant amount to the study. Every time I hear about a new investor, it's music to my ears. Metformin Is the Tool, Not the Goal Installing insulation in your attic or weather stripping …

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Excessive feelings of shame, depression, or anxiety

After the meeting, Robert Temple, deputy center director for clinical science for the FDA's Center for Drug Evaluation and Research, commented for Ron Howard's The Age of Aging, a documentary about the science of aging: Loss of muscle tone, dizziness, falling, dementia, loss of eyesight, all those things--to [approach] them …

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Focus Your Attention Better

Fortunately, we have AFAR as a partner. My history with AFAR goes back to 1996, when the field of aging studies was sparsely populated and the organization gave me my first grant, which allowed me to gather the data I needed to then get an NIH grant for much more …

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Intense fear of failure

Who's Going to Pay for All of This? We had thought that designing the study would be the hardest part of the battle. Once again, we were wrong. Stufft added, You have done so much to help the school help the environment and help the planet. This stance of service …

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Negative experiences don't impact overall perspective

After the conference in Spain, the evidence in metformin's favor became overwhelming. In addition to the safety factor--metformin has sixty-plus years of safe use, compared with the unresolved safety issues of many other drugs that can target aging--new clinical trials reported significant reductions in the risk for type 2 diabetes …

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Trouble accepting positive feedback

We're also collecting data on common geriatric conditions, such as fractures and pneumonia, and syndromes, such as frailty and fall-related injuries. When TAME concludes, this information will be made available to the broad research community and health care providers to guide and accelerate the pace of applied geroscience. Although functional …

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Examples of High Self-Esteem

When we decided to form the company, we promised each other that we would not make the same mistakes that put 95 percent of biotech start-ups out of business. And while that success rate didn't sound promising, because we are both M. We also had the benefit of having served …

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Factors That Influence Self-Esteem

Such damage may be initiated in part when telomeres (DNA strands at the end of chromosomes) get shorter. Senescence: Len Hayflick has shown that there are limits to the number of times a cell can divide. When cells divide for the last time, their appearance and functions change, and these …

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Incorporating Self-Esteem in Positive Psychology

For the past few years, Jerry has devoted much of his time to his role as Bernice's caregiver. They moved into a continuing care center after she suffered a stroke, and as his son-in-law and a scientist studying SuperAgers, it's rewarding for me to see the determination he's able to …

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Tips & Affirmations for Enhancing Self-Esteem

It's immune dysfunction that makes viruses like Coronavirus life-threatening to the elderly. After they have the virus for a few days their immune systems create an immunological storm that causes the clinical features that can lead to death. Rejuvenating the immune response may lower or eliminate this effect on the …

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What is the Meaning of Self-esteem?

So he took a job as a controller with a trucking company that offered more opportunity, and he remained in the trucking industry until the early '80s--a career during which he achieved his goal of financial independence and negotiated with Teamsters president Jimmy Hoffa. You'd tell him beforehand what it …

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Institutions and women

But instead of being disoriented by our surprise visit, when we explained things to her, she would say something to the effect of This is so great, because I'm pleasantly surprised twice--when you call and when you arrive. Frieda died in 2008 at age 102. One of her siblings had …

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People Principles

She lived by her own rules, as her son Jerry Rubenstein (my father-in-law) attests. The poker games went on for years, and there was a game where she began laughing or giggling at the table and someone who was taking it too seriously criticized her for it, he says. So …

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Spirit of Self-Help

I mean, I called it unrealistic, but it was supported by her lifetime of experiences. Hand in hand with her optimism was a refusal to take things more seriously than necessary--a refusal to take on more stress than necessary. In that regard, she and Jerry--both participants in our study of …

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Elicit Your Own Acknowledgement

While farmers markets are far from perfect, they're still a solid alternative to growing your own food. Purchasing a farm share in a community supported agriculture (CSA) program provides even more direct support to farmers. The CSA we participated in allowed us to choose which fruits and vegetables we wanted …

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How to Melt Hard Feelings

Just participating in the process of growing helps kids realize how much work goes into producing their fruits and vegetables. They understand how hard it is to go from farm to plate, said Fisher. To see that food takes time, tending, sun, soil, water, and air is a pretty refreshing …

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Right Makes Might

Since my own kids have been big enough to have opinions, I've worked with them to plan our garden. In the winter, we look at the seed catalog together and they make suggestions about what types of seeds to buy. Asking kids for their ideas and listening to their perspectives …

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The Bad Apples

They may still swipe your tools, but at least you'll have extras. It's great if you can set aside a space for kids to do whatever they want. In our yard, we have a small raised bed that our kids plant and dig in. We've planted giant sunflowers with enough …

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How to Be Close to Your Friends

Children and families are more connected and are working together. Similarly, Nicholes said that both her home garden and the We Sow, We Grow community farm are places her family can spend time together without planned activities. I do think that in society, we're losing that ability to have togetherness …

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How to Have More Life in Your Time

Folks now realize that our space is a safe place for them to come and talk and be curious without feeling like they're being a burden on anyone, she said. For people to see folks smack-dab in the middle of the city, growing food, their curiosity gets the better of …

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Is That Clear?

I've never seen spinach or lettuce ripped so thoroughly. Each time the salad spinner or glass jar came around, they put some serious muscle into it. As the kids prepped each ingredient, they tossed it into a big bowl, combining it into one giant salad. As we finished, the instructors …

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Necessary Conflict

Empowered by having real tools, the kids went to town. We next moved on to kale, the much-maligned hipster green. But we were going to do something a little different here. Do we eat flowers? When the kids looked confused, she said, We can eat these! Pick two yellow kale …

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Personality Myth

Having searched for flowers, it was time for us to plant our own. Gathering the kids around an empty patch of dirt, the instructor knelt down with a trowel. Just dig up a little bit of dirt, she said as she pushed some soil aside. Take a few flower seeds …

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Suggestive Moves

In a long-term garden project, there's even less immediate gratification. There's also something nice about gardening that it's kind of time released in terms of your experience of it, said Fisher, talking about his experience at Life Lab and his son's school garden. It's a different way to experience things …

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Take the Sting Out of It

In the Youth Garden's Green Ambassadors program for high school students, participants cook a meal each Friday for the entire staff with produce from the garden. Building Relationships and Service to Others With the food eaten and the program over, it was time to go home. But I still had …

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To Zip or Not to Zip

The kids are interested in different varieties of tomatoes and ask questions about whether they're heat resistant or not--an essential characteristic during hot Chicago summers. She said, I'm loving the fact that the kids are thinking about their food in a different way. But also learning to love what they …

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We're Family

She saw the effects gardening had on the women: it helped them reduce their stress levels, develop more empathy, and manage their anger. A lot of them saw significant changes in themselves as a result of participating in the gardening project, she said. Many of the women applied the ideas …

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